Flutemetamol F-18
2-[3-(18F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol
Molecular Identity
Flutemetamol F-18
2-[3-(18F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol
PubChem CID: 15950376
Flutemetamol ((18)F) is a member of the class of benzothiazoles that is 1,3-benzothiazole substituted by 3-(18F)fluoro-4-(methylamino)phenyl and hydroxy groups at positions 3 and 6 respectively. A positron emission tomography imaging ligand for the detection of amyloid aggregation associated with Alzheimer disease. It has a role as a radioactive imaging agent. It is an aromatic amine, a member of benzothiazoles, a (18)F radiopharmaceutical and a secondary amino compound.
2D Structure
Properties
C14H11FN2OS
Molecular Formula
273.32
Molecular Weight
g/mol
273.0601
Exact Mass
Da
3.8
XLogP
Drug-like (Lipinski: < 5)
73.4
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
5
H-Bond Acceptors
320
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Flutemetamol F-18flutemetamol (18F)VizamylFlutemetamol F18[18F]flutemetamol(18f)flutemetamolL49M066S0Oflutemetamol ((18)F)AH-110690 F-18CHEBI:76611flutemetamolum (18F)RefChem:56832V09AX042-(3-(1?F)fluoro-4-(methylamino)phenyl)-1,3-benzothiazol-6-olFlutemetamol F 18
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Flutemetamol F-18
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