Segigratinib
N-[6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo[5,4-b]pyridin-3-yl]-4-(3,3-dimethylpiperazin-1-yl)benzamide
Molecular Identity
Segigratinib
N-[6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo[5,4-b]pyridin-3-yl]-4-(3,3-dimethylpiperazin-1-yl)benzamide
PubChem CID: 118893637
2D Structure
Properties
C27H28Cl2N6O3
Molecular Formula
555.50
Molecular Weight
g/mol
554.1600
Exact Mass
Da
4.9
XLogP
Drug-like (Lipinski: < 5)
104
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
7
H-Bond Acceptors
800
Complexity
SMILES
Canonical SMILES
SMILES: CC1(CN(CCN1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3C=CC(=N4)C5=C(C(=CC(=C5Cl)OC)OC)Cl)CIsomeric SMILES
SMILES: CC1(CN(CCN1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3C=CC(=N4)C5=C(C(=CC(=C5Cl)OC)OC)Cl)CSynonyms(20)
segigratinib1882873-93-93D185Ratangratinib3D-185ratangratinib [INN]HH185 FREE BASE3D185 FREE BASEG0Z5E4YTB4HH-185 FREE BASE3D-185 FREE BASEorb2663923CHEMBL5269917SCHEMBL17530933GTPL13218
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Segigratinib
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