Sirusertib
6-[(1-methylindazol-5-yl)amino]-1-[6-(1-methylpiperidin-4-yl)oxy-2-pyridinyl]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
Molecular Identity
Sirusertib
6-[(1-methylindazol-5-yl)amino]-1-[6-(1-methylpiperidin-4-yl)oxy-2-pyridinyl]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
PubChem CID: 172628816
2D Structure
Properties
C27H29N9O2
Molecular Formula
511.60
Molecular Weight
g/mol
511.2444
Exact Mass
Da
4
XLogP
Drug-like (Lipinski: < 5)
105
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
9
H-Bond Acceptors
839
Complexity
SMILES
Canonical SMILES
SMILES: CN1CCC(CC1)OC2=CC=CC(=N2)N3C4=NC(=NC=C4C(=O)N3CC=C)NC5=CC6=C(C=C5)N(N=C6)CIsomeric SMILES
SMILES: CN1CCC(CC1)OC2=CC=CC(=N2)N3C4=NC(=NC=C4C(=O)N3CC=C)NC5=CC6=C(C=C5)N(N=C6)CSynonyms(7)
sirusertibSCHEMBL31304379SCHEMBL31304672GTPL14633ACR-2316compound 109 [WO2024254490]6-[(1-methylindazol-5-yl)amino]-1-[6-(1-methylpiperidin-4-yl)oxy-2-pyridinyl]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Sirusertib
Loading drug network...