PF-Akt400
N-[[(3S)-3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl]-2,4-difluorobenzamide
Molecular Identity
PF-Akt400
N-[[(3S)-3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl]-2,4-difluorobenzamide
PubChem CID: 25061501
2D Structure
Properties
C20H22F2N6O
Molecular Formula
400.40
Molecular Weight
g/mol
400.1823
Exact Mass
Da
2.2
XLogP
Drug-like (Lipinski: < 5)
99.9
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
7
H-Bond Acceptors
597
Complexity
SMILES
Canonical SMILES
SMILES: CCC1=CNC2=C1C(=NC=N2)N3CCC(C3)(CNC(=O)C4=C(C=C(C=C4)F)F)NIsomeric SMILES
SMILES: CCC1=CNC2=C1C(=NC=N2)N3CC[C@@](C3)(CNC(=O)C4=C(C=C(C=C4)F)F)NSynonyms(20)
1004990-28-6PF-AKT400akt inhibitorAKT protein kinase inhibitor(S)-N-[[3-Amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl]-2,4-difluorobenzamideAKT-0286N-{[(3s)-3-Amino-1-(5-Ethyl-7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)pyrrolidin-3-Yl]methyl}-2,4-DifluorobenzamideCHEMBL1171647N-[[(3S)-3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl]-2,4-difluorobenzamideBenzamide, N-[[(3S)-3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-pyrrolidinyl]methyl]-2,4-difluoro-(S)-N-((3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)methyl)-2,4-difluorobenzamideYB5ERF8F5Q1L-6-HYDROXYMETHYL-CHIRO-INOSITOL 2-(R)-2-O-METHYL-3-O-OCTADECYLCARBONATEorb1227175orb1301735
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to PF-Akt400
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