AMG410
(26S)-18-chloro-32-fluoro-4-[[(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]-23,25,28-trioxa-1,3,5,9,14,15-hexazahexacyclo[24.4.1.16,10.02,7.011,19.012,16]dotriaconta-2,4,6(32),7,9,11,13,16,18-nonaen-24-one
Molecular Identity
AMG410
(26S)-18-chloro-32-fluoro-4-[[(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]-23,25,28-trioxa-1,3,5,9,14,15-hexazahexacyclo[24.4.1.16,10.02,7.011,19.012,16]dotriaconta-2,4,6(32),7,9,11,13,16,18-nonaen-24-one
PubChem CID: 172142898
2D Structure
Properties
C31H32ClF2N7O5
Molecular Formula
656.10
Molecular Weight
g/mol
655.2122
Exact Mass
Da
4.3
XLogP
Drug-like (Lipinski: < 5)
128
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
13
H-Bond Acceptors
1110
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(14)
AMG4103040175-17-2(16S)-36-Chloro-28-fluoro-22-(((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)-31H-7,9-dioxa-1(4,6)-oxazepana-2(4,7)-pyrido[4,3-d]pyrimidina-3(4,5)-indazolacyclononaphan-8-oneorb2946000SCHEMBL30922748GTPL14131AMG 410AMG-410BDBM694933EX-A12455AT48450example 99 [WO2024107686]US20240294551, Example 99US20240294551, Example 341
Data from PubChem (NCBI)
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