ARV-471
(3S)-3-[6-[4-[[1-[4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
Molecular Identity
ARV-471
(3S)-3-[6-[4-[[1-[4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
PubChem CID: 134562533
2D Structure
Properties
C45H49N5O4
Molecular Formula
723.90
Molecular Weight
g/mol
723.3785
Exact Mass
Da
6.4
XLogP
Above Lipinski threshold
96.4
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
7
H-Bond Acceptors
1310
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
ARV-471VepdegestrantARV471ARV-471 (protac)Arv 471PF-07850327PF07850327RefChem:199635PROTAC Protein Degrader ARV-471ER alpha PROTAC Protein Degrader ARV-471PF 07850327Estrogen Receptor alpha PROTAC Protein Degrader ARV-471ER alpha Proteolysis-targeting Chimera Protein Degrader ARV-4712229711-68-4WC1U3R1YMI
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to ARV-471
Loading drug network...