Aumolertinib
N-[5-[[4-(1-cyclopropylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]-4-methoxyphenyl]prop-2-enamide
Molecular Identity
Aumolertinib
N-[5-[[4-(1-cyclopropylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]-4-methoxyphenyl]prop-2-enamide
PubChem CID: 121280087
2D Structure
Properties
C30H35N7O2
Molecular Formula
525.60
Molecular Weight
g/mol
525.2852
Exact Mass
Da
4.2
XLogP
Drug-like (Lipinski: < 5)
87.6
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
7
H-Bond Acceptors
823
Complexity
SMILES
Canonical SMILES
SMILES: CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C5CC5)OCIsomeric SMILES
SMILES: CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C5CC5)OCSynonyms(20)
Almonertinib1899921-05-1HS-10296AumolertinibAmeileEgfr T790M inhibitor HS-10296T4RS462G19EQ143EQ-143Hs 102962-Propenamide, N-(5-((4-(1-cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl)amino)-2-((2-(dimethylamino)ethyl)methylamino)-4-methoxyphenyl)-2-Propenamide, N-[5-[[4-(1-cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-RefChem:115556EGFR Tyrosine Kinase Inhibitor HS-10296HS-10297
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Aumolertinib
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