AZD0022
4-[4-[(1R,5S)-3,8-diazabicyclo[3.2.1]oct-6-en-3-yl]-6,8-difluoro-2-[[(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]quinazolin-7-yl]-5-ethynyl-6-fluoronaphthalen-2-amine
Molecular Identity
AZD0022
4-[4-[(1R,5S)-3,8-diazabicyclo[3.2.1]oct-6-en-3-yl]-6,8-difluoro-2-[[(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]quinazolin-7-yl]-5-ethynyl-6-fluoronaphthalen-2-amine
PubChem CID: 172991795
2D Structure
Properties
C34H30F4N6O
Molecular Formula
614.60
Molecular Weight
g/mol
614.2417
Exact Mass
Da
5.6
XLogP
Above Lipinski threshold
79.5
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
11
H-Bond Acceptors
1170
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(4)
AZD0022EX-A12456AT484774-[4-[(1R,5S)-3,8-diazabicyclo[3.2.1]oct-6-en-3-yl]-6,8-difluoro-2-[[(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]quinazolin-7-yl]-5-ethynyl-6-fluoronaphthalen-2-amine
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to AZD0022
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