AZD1480
5-chloro-2-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Molecular Identity
AZD1480
5-chloro-2-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
PubChem CID: 16659841
2D Structure
Properties
C14H14ClFN8
Molecular Formula
348.76
Molecular Weight
g/mol
348.1014
Exact Mass
Da
2.4
XLogP
Drug-like (Lipinski: < 5)
104
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
8
H-Bond Acceptors
397
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
AZD1480935666-88-9AZD-1480AZD 1480KL2Z2TLF015-Chloro-N2-[(1s)-1-(5-Fluoropyrimidin-2-Yl)ethyl]-N4-(5-Methyl-1h-Pyrazol-3-Yl)pyrimidine-2,4-DiamineDTXSID502394692,4-Pyrimidinediamine, 5-chloro-N2-((1S)-1-(5-fluoro-2-pyrimidinyl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)-5-chloro-2-N-((1S)-1-(5-fluoropyrimidin-2-yl)ethyl)-4-N-(3-methyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine5-chloro-2-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(3-methyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine5-chloro-N2-((1S)-1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamineRefChem:115989DTXCID20161960JAK2 INHIBITOR AZD1480(S)-5-chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Data from PubChem (NCBI)
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