Azd-4604
(2R)-N-[3-[5-fluoro-2-(2-fluoro-3-methylsulfonylanilino)pyrimidin-4-yl]-1H-indol-7-yl]-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide
Molecular Identity
Azd-4604
(2R)-N-[3-[5-fluoro-2-(2-fluoro-3-methylsulfonylanilino)pyrimidin-4-yl]-1H-indol-7-yl]-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide
PubChem CID: 135240395
2D Structure
Properties
C28H31F2N7O4S
Molecular Formula
599.70
Molecular Weight
g/mol
599.2126
Exact Mass
Da
2.2
XLogP
Drug-like (Lipinski: < 5)
141
TPSA
May have limited oral absorption
3
H-Bond Donors
11
H-Bond Acceptors
1010
Complexity
SMILES
Canonical SMILES
SMILES: CN1CCN(CC1)C(COC)C(=O)NC2=CC=CC3=C2NC=C3C4=NC(=NC=C4F)NC5=C(C(=CC=C5)S(=O)(=O)C)FIsomeric SMILES
SMILES: CN1CCN(CC1)[C@H](COC)C(=O)NC2=CC=CC3=C2NC=C3C4=NC(=NC=C4F)NC5=C(C(=CC=C5)S(=O)(=O)C)FSynonyms(20)
JAK1-IN-72241039-81-4londamocitinibAZD4604AZD-4604JAC34RRR7S(2R)-N-[3-[5-fluoro-2-(2-fluoro-3-methylsulfonylanilino)pyrimidin-4-yl]-1H-indol-7-yl]-3-methoxy-2-(4-methylpiperazin-1-yl)propanamideexample 35 [WO2018134213A1]1-Piperazineacetamide, N-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1H-indol-7-yl)-alpha-(methoxymethyl)-4-methyl-, (alphaR)-example 35 (WO2018134213A1)(2R)-N-(3-(5-fluoro-2-(2-fluoro-3-methylsulfonylanilino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide1-Piperazineacetamide, N-[3-[5-fluoro-2-[[2-fluoro-3-(methylsulfonyl)phenyl]amino]-4-pyrimidinyl]-1H-indol-7-yl]-alpha-(methoxymethyl)-4-methyl-, (alphaR)-RefChem:1996811-PIPERAZINEACETAMIDE, N-(3-(5-FLUORO-2-((2-FLUORO-3-(METHYLSULFONYL)PHENYL)AMINO)-4-PYRIMIDINYL)-1H-INDOL-7-YL)-.ALPHA.-(METHOXYMETHYL)-4-METHYL-, (.ALPHA.R)-(R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Azd-4604
Loading drug network...