Utatrectinib
N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-3-(3-propan-2-yloxy-1H-pyrazol-5-yl)imidazo[4,5-b]pyridin-5-amine
Molecular Identity
Utatrectinib
N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-3-(3-propan-2-yloxy-1H-pyrazol-5-yl)imidazo[4,5-b]pyridin-5-amine
PubChem CID: 25115967
2D Structure
Properties
C18H19FN8O
Molecular Formula
382.40
Molecular Weight
g/mol
382.1666
Exact Mass
Da
2.7
XLogP
Drug-like (Lipinski: < 5)
106
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
8
H-Bond Acceptors
506
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)OC1=NNC(=C1)N2C=NC3=C2N=C(C=C3)NC(C)C4=NC=C(C=N4)FIsomeric SMILES
SMILES: C[C@@H](C1=NC=C(C=N1)F)NC2=NC3=C(C=C2)N=CN3C4=CC(=NN4)OC(C)CSynonyms(20)
utatrectinib1079274-94-4AZD-7451AZD7451VNM956Y27VRefChem:116016TRK Inhibitor AZD7451Tropomyosin Receptor Kinase Inhibitor AZD7451UNII-VNM956Y27VN-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-3-(3-propan-2-yloxy-1H-pyrazol-5-yl)imidazo[4,5-b]pyridin-5-amine(S)-N-(1-(5-Fluoropyrimidin-2-yl)ethyl)-3-(5-isopropoxy-1H-pyrazol-3-yl)-3H-imidazo[4,5-b]pyridin-5-amineAYOOGWWGECJQPI-NSHDSACASA-NN-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-3-[5-(propan-2-yloxy)-1H-pyrazol-3-yl]-3H-imidazo[4,5-b]pyridin-5-amineUTATRECTINIB [INN]orb1737996
Data from PubChem (NCBI)
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Trials and conditions connected to Utatrectinib
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