Molecular Identity
QUINAPRIL HYDROCHLORIDE
(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid;hydrochloride
PubChem CID: 54891
Quinapril hydrochloride is a hydrochloride resulting from the reaction of equimolar amounts of quinapril and hydrogen chloride. A prodrug for quinaprilat hydrochloride (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and an antihypertensive agent. It contains a quinapril(1+).
2D Structure
Properties
C25H31ClN2O5
Molecular Formula
475.00
Molecular Weight
g/mol
474.1921
Exact Mass
Da
95.9
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
6
H-Bond Acceptors
648
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
QUINAPRIL HYDROCHLORIDE82586-55-8QUINAPRIL HCLKorecAccuprinQuinazilAcequinAcuitelHemokvinAccuproCI-906DTXSID3021221CI 906NSC-75822233067B3N2M
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to QUINAPRIL HYDROCHLORIDE
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