Molecular Identity
AMILORIDE
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
PubChem CID: 16231
Amiloride is a member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid. It has a role as a diuretic and a sodium channel blocker. It is a member of guanidines, an aromatic amine, an organochlorine compound and a member of pyrazines. It is a conjugate base of an amiloride(1+).
2D Structure
Properties
C6H8ClN7O
Molecular Formula
229.63
Molecular Weight
g/mol
229.0479
Exact Mass
Da
-0.7
XLogP
Drug-like (Lipinski: < 5)
159
TPSA
May have limited oral absorption
4
H-Bond Donors
5
H-Bond Acceptors
279
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
AMILORIDEAmipramidin2609-46-3GuanamprazinAmiloridaAmipramizid3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamideAmiloridumMidamorAmiclaranN-Amidino-3,5-diamino-6-chloropyrazinecarboxamide3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide7DZO8EB0Z3DTXSID9043853Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to AMILORIDE
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