Molecular Identity
Amprenavir
[(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
PubChem CID: 65016
Amprenavir is a carbamate ester, a sulfonamide and a tetrahydrofuryl ester. It has a role as a HIV protease inhibitor and an antiviral drug.
2D Structure
Properties
C25H35N3O6S
Molecular Formula
505.60
Molecular Weight
g/mol
505.2247
Exact Mass
Da
2.9
XLogP
Drug-like (Lipinski: < 5)
140
TPSA
May have limited oral absorption
3
H-Bond Donors
8
H-Bond Acceptors
745
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)O)S(=O)(=O)C3=CC=C(C=C3)NIsomeric SMILES
SMILES: CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CCOC2)O)S(=O)(=O)C3=CC=C(C=C3)NSynonyms(20)
amprenavir161814-49-9AgeneraseVX-478Prozei141W94KVX-478Vertex VX478VX 4785S0W860XNR(3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamateCHEBI:40050J05AE05Tetrahydro-3-furyl N-(3-(4-amino-N-isobutylbenzenesulfonamido)-1-benzyl-2-hydroxypropyl)carbamate(3S-(3R*(1R*,2S*)))-(3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl) tetrahydro-3-furanyl carbamate
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Amprenavir
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