Artesunate
4-oxo-4-[[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid
Molecular Identity
Artesunate
4-oxo-4-[[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid
PubChem CID: 6917864
Artesunate is an artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria. It has a role as a ferroptosis inducer, an antineoplastic agent and an antimalarial. It is a hemisuccinate, a sesquiterpenoid, a dicarboxylic acid monoester, a cyclic acetal, an artemisinin derivative and a semisynthetic derivative.
2D Structure
Properties
C19H28O8
Molecular Formula
384.40
Molecular Weight
g/mol
384.1784
Exact Mass
Da
2.5
XLogP
Drug-like (Lipinski: < 5)
101
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
8
H-Bond Acceptors
623
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
ArtesunateArtesunic acid88495-63-0ArsumaxPlasmotrinQinghaozhiSaphnateArtesunatoArtesunatumDihydroqinghasu hemsuccinateZysunateWR 256283Dihydroqinghaosu hemisuccinateCHEBI:63918LJPC-0118
Data from PubChem (NCBI)
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