Molecular Identity
Artemether
(1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
PubChem CID: 68911
Artemether is an artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial. It is an organic peroxide, a sesquiterpenoid, a cyclic acetal, an artemisinin derivative and a semisynthetic derivative.
2D Structure
Properties
C16H26O5
Molecular Formula
298.37
Molecular Weight
g/mol
298.1780
Exact Mass
Da
3.1
XLogP
Drug-like (Lipinski: < 5)
46.2
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
5
H-Bond Acceptors
429
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Artemether71963-77-4beta-ArtemetherDihydroartemisinin methyl etherArtemeteroArtemetherumArtesaphFalcidolMalartemPalutherGvitherMethyl-dihydroartemisinineArtemisininelactol methyl etherArtemetheriLarither
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Artemether
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