BLU-222
N-[3-(difluoromethoxy)-1H-pyrazol-5-yl]-1-(oxan-4-ylmethyl)pyrazolo[3,4-b]pyrazin-6-amine
Molecular Identity
BLU-222
N-[3-(difluoromethoxy)-1H-pyrazol-5-yl]-1-(oxan-4-ylmethyl)pyrazolo[3,4-b]pyrazin-6-amine
PubChem CID: 168752082
2D Structure
Properties
C15H17F2N7O2
Molecular Formula
365.34
Molecular Weight
g/mol
365.1412
Exact Mass
Da
2.1
XLogP
Drug-like (Lipinski: < 5)
103
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
9
H-Bond Acceptors
458
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
BLU-2222888704-84-3CertociclibBLU222CDK2 Inhibitor BLU-222BLU170298BLU-170298U93X72ED47RefChem:1081369BLU 222CirtociclibCertociclib (USAN)CERTOCICLIB [USAN]N-(5-(Difluoromethoxy)-1H-pyrazol-3-yl)-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazolo[3,4-b]pyrazin-6-amineN-[3-(difluoromethoxy)-1H-pyrazol-5-yl]-1-(oxan-4-ylmethyl)pyrazolo[3,4-b]pyrazin-6-amine
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to BLU-222
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