CC-99677
(15R)-5-[2-chloro-5-(ethoxymethyl)pyrimidin-4-yl]oxy-15-methyl-11-thia-6,14,17-triazatetracyclo[8.8.0.02,7.012,18]octadeca-1(10),2(7),3,5,8,12(18)-hexaen-13-one
Molecular Identity
CC-99677
(15R)-5-[2-chloro-5-(ethoxymethyl)pyrimidin-4-yl]oxy-15-methyl-11-thia-6,14,17-triazatetracyclo[8.8.0.02,7.012,18]octadeca-1(10),2(7),3,5,8,12(18)-hexaen-13-one
PubChem CID: 118936948
2D Structure
Properties
C22H20ClN5O3S
Molecular Formula
469.90
Molecular Weight
g/mol
469.0975
Exact Mass
Da
4.5
XLogP
Drug-like (Lipinski: < 5)
127
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
8
H-Bond Acceptors
677
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
CC-99677Gamcemetinib1887069-10-4OS2IR8TV1OBMS-986371RefChem:1085680(R)-3-((2-Chloro-5-(ethoxymethyl)pyrimidin-4-yl)oxy)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-oneGamcemetinib (USAN)GAMCEMETINIB [USAN]gamcemetinib [INN]orb1691401CHEMBL5314585SCHEMBL17581285SCHEMBL30575045GTPL12167
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to CC-99677
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