Zeteletinib
2-[6-(6,7-dimethoxyquinolin-3-yl)-3-pyridinyl]-N-[3-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-5-yl]acetamide
Molecular Identity
Zeteletinib
2-[6-(6,7-dimethoxyquinolin-3-yl)-3-pyridinyl]-N-[3-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-5-yl]acetamide
PubChem CID: 134391533
2D Structure
Properties
C25H23F3N4O4
Molecular Formula
500.50
Molecular Weight
g/mol
500.1671
Exact Mass
Da
4.6
XLogP
Drug-like (Lipinski: < 5)
99.4
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
10
H-Bond Acceptors
755
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)(C1=NOC(=C1)NC(=O)CC2=CN=C(C=C2)C3=CN=C4C=C(C(=CC4=C3)OC)OC)C(F)(F)FIsomeric SMILES
SMILES: CC(C)(C1=NOC(=C1)NC(=O)CC2=CN=C(C=C2)C3=CN=C4C=C(C(=CC4=C3)OC)OC)C(F)(F)FSynonyms(20)
Zeteletinib2216753-97-6BOS-172738Ret inhibitor DS-5010Zeteletinib [INN]Zeteletinib [USAN]CAXM-1190bBOS172738DS-5010bEP0P7SHM0UBOS172738 free baseBOS-172738 free base2-[6-(6,7-dimethoxyquinolin-3-yl)pyridin-3-yl]-N-[3-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-5-yl]acetamideZeteletinib (USAN)Example 3 [WO2018060714A1]
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Zeteletinib
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