Ambrisentan
(2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
Molecular Identity
Ambrisentan
(2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
PubChem CID: 6918493
Ambrisentan is a diarylmethane.
2D Structure
Properties
C22H22N2O4
Molecular Formula
378.40
Molecular Weight
g/mol
378.1580
Exact Mass
Da
3.8
XLogP
Drug-like (Lipinski: < 5)
81.5
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
6
H-Bond Acceptors
475
Complexity
SMILES
Canonical SMILES
SMILES: CC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)CIsomeric SMILES
SMILES: CC1=CC(=NC(=N1)O[C@H](C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)CSynonyms(20)
Ambrisentan177036-94-1LetairisVolibrisLU-208075BSF-208075DTXSID4046282HW6NV07QECGSK1325760AGSK-1325760AGSK1325760GSK-1325760DTXCID2026282(2s)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid(+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Ambrisentan
Loading drug network...