Molecular Identity
Bendroflumethiazide
3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
PubChem CID: 2315
Bendroflumethiazide is a sulfonamide consisting of 7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by a trifluoromethyl group and that at position 3 is substituted by a benzyl group. It has a role as a diuretic and an antihypertensive agent. It is a sulfonamide and a benzothiadiazine.
2D Structure
Properties
C15H14F3N3O4S2
Molecular Formula
421.40
Molecular Weight
g/mol
421.0378
Exact Mass
Da
1.2
XLogP
Drug-like (Lipinski: < 5)
135
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
10
H-Bond Acceptors
740
Complexity
SMILES
Canonical SMILES
SMILES: C1=CC=C(C=C1)CC2NC3=C(C=C(C(=C3)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N2Isomeric SMILES
SMILES: C1=CC=C(C=C1)CC2NC3=C(C=C(C(=C3)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N2Synonyms(20)
BENDROFLUMETHIAZIDEBendrofluazide73-48-3NaturetinAprinoxBenzhydroflumethiazideBenzylrodiuranCentylPlurylBentrideBristuricBristuronFlumesilNiagarilPlusuril
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Bendroflumethiazide
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