Betrixaban
N-(5-chloro-2-pyridinyl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide
Molecular Identity
Betrixaban
N-(5-chloro-2-pyridinyl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide
PubChem CID: 10275777
Betrixaban is a secondary carboxamide obtained by formal condensation of the carboxy group of 4-(N,N-dimethylcarbamimidoyl)benzoic acid with the amino group of 2-amino-N-(5-chloropyridin-2-yl)-5-methoxybenzamide. A synthetic anticoagulant compound that targets activated factor Xa in the coagulation cascade. It has a role as an anticoagulant and an EC 3.4.21.6 (coagulation factor Xa) inhibitor. It is a secondary carboxamide, a member of benzamides, a member of guanidines, a monomethoxybenzene and a monochloropyridine.
2D Structure
Properties
C23H22ClN5O3
Molecular Formula
451.90
Molecular Weight
g/mol
451.1411
Exact Mass
Da
3.6
XLogP
Drug-like (Lipinski: < 5)
107
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
5
H-Bond Acceptors
668
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Betrixaban330942-05-7PRT054021N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamidePRT 054021PRT-05402174RWP7W0J9N-(5-Chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamideCHEBI:140421DTXSID10954727N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamideBenzamide, N-(5-chloro-2-pyridinyl)-2-((4-((dimethylamino)iminomethyl)benzoyl)amino)-5-methoxy-betrixabanumN-(5-CHLOROPYRIDIN-2-YL)-2-((4-(N,N-DIMETHYLCARBAMIMIDOYL)BENZOYL)AMINO)-5-METHOXYBENZAMIDERefChem:58846
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Betrixaban
Loading drug network...