clodronate disodium tetrahydrate
disodium;[dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate;tetrahydrate
Molecular Identity
clodronate disodium tetrahydrate
disodium;[dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate;tetrahydrate
PubChem CID: 23724874
Disodium clodronate tetrahydrate is the tetrahydrate of the disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases. It has a role as a bone density conservation agent. It is a hydrate and a one-carbon compound. It contains a clodronic acid disodium salt.
2D Structure
Properties
CH10Cl2Na2O10P2
Molecular Formula
360.91
Molecular Weight
g/mol
359.8922
Exact Mass
Da
125
TPSA
Good oral absorption (< 140 A²)
6
H-Bond Donors
10
H-Bond Acceptors
206
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
clodronate disodium tetrahydrateBonefosCLODRONATE DISODIUMPhosphonic acid, (dichloromethylene)bis-, disodium salt, tetrahydrateClodronic acid disodium tetrahydrateClodronic acid disodium salt tetrahydrateZk-00091106Sodium clodronate hydrateZK 00091106N030400H8J(Dichloromethylene)bisphosphonate disodium tetrahydrateDTXSID40237035NSC713466DifosfonalSodium, Clodronate
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to clodronate disodium tetrahydrate
Loading drug network...