CFT1946
(3R)-3-[6-[2-cyano-3-[[ethyl(methyl)sulfamoyl]amino]-6-fluorophenoxy]-4-oxoquinazolin-3-yl]-8-[2-[1-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-4-hydroxypiperidin-4-yl]acetyl]-1-oxa-8-azaspiro[4.5]decane
Molecular Identity
CFT1946
(3R)-3-[6-[2-cyano-3-[[ethyl(methyl)sulfamoyl]amino]-6-fluorophenoxy]-4-oxoquinazolin-3-yl]-8-[2-[1-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-4-hydroxypiperidin-4-yl]acetyl]-1-oxa-8-azaspiro[4.5]decane
PubChem CID: 166168413
2D Structure
Properties
C45H49F2N11O9S
Molecular Formula
958.00
Molecular Weight
g/mol
957.3403
Exact Mass
Da
2.7
XLogP
Drug-like (Lipinski: < 5)
244
TPSA
May have limited oral absorption
3
H-Bond Donors
17
H-Bond Acceptors
2110
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(19)
CFT19462882165-79-7CFT-1946N'-[2-Cyano-4-fluoro-3-[[3-[(3R)-8-[2-[1-[5-fluoro-1-methyl-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)-1H-indazol-6-yl]-4-hydroxy-4-piperidinyl]acetyl]-1-oxa-8-azaspiro[4.5]dec-3-yl]-3,4-dihydro-4-oxo-6-quinazolinyl]oxy]phenyl]-N-ethyl-N-methylsulfamideGTPL12623(3R)-3-[6-[2-cyano-3-[[ethyl(methyl)sulfamoyl]amino]-6-fluorophenoxy]-4-oxoquinazolin-3-yl]-8-[2-[1-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-4-hydroxypiperidin-4-yl]acetyl]-1-oxa-8-azaspiro[4.5]decaneTagarafdegtagarafdeg [INN]TT8PCR57MKorb2278978SCHEMBL24752780SCHEMBL30120194GLXC-27385EX-A7771AT41377
Data from PubChem (NCBI)
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