Gdc-0917
(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[2-(1,3-oxazol-2-yl)-4-phenyl-1,3-thiazol-5-yl]pyrrolidine-2-carboxamide
Molecular Identity
Gdc-0917
(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[2-(1,3-oxazol-2-yl)-4-phenyl-1,3-thiazol-5-yl]pyrrolidine-2-carboxamide
PubChem CID: 71600094
2D Structure
Properties
C29H36N6O4S
Molecular Formula
564.70
Molecular Weight
g/mol
564.2519
Exact Mass
Da
4
XLogP
Drug-like (Lipinski: < 5)
158
TPSA
May have limited oral absorption
3
H-Bond Donors
8
H-Bond Acceptors
883
Complexity
SMILES
Canonical SMILES
SMILES: CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=C(S3)C4=NC=CO4)C5=CC=CC=C5)NCIsomeric SMILES
SMILES: C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C(=O)NC3=C(N=C(S3)C4=NC=CO4)C5=CC=CC=C5)NCSynonyms(20)
GDC-0917UNII-KWH46ZDG32(2S)-1-((2S)-2-cyclohexyl-2-((2S)-2-(methylamino)propanamido)acetyl)-N-(2-(1,3-oxazol-2-yl)-4-phenyl-1,3-thiazol-5-yl)pyrrolidine-2-carboxamide(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)propanamido]acetyl]-N-[2-(1,3-oxazol-2-yl)-4-phenyl-1,3-thiazol-5-yl]pyrrolidine-2-carboxamideRefChem:142769CUDC427IAP Antagonist GDC-0917SMAC MIMETIC GDC-0917SMAC/DIABLO Mimetic GDC-0917RG7459RG 7459RG-7459CUDC-4271446182-94-0Cudc 427
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Gdc-0917
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