Mefuparib hydrochloride
5-fluoro-2-[4-(methylaminomethyl)phenyl]-1-benzofuran-7-carboxamide;hydrochloride
Molecular Identity
Mefuparib hydrochloride
5-fluoro-2-[4-(methylaminomethyl)phenyl]-1-benzofuran-7-carboxamide;hydrochloride
PubChem CID: 117734810
Mefuparib hydrochloride is the hydrochloride salt of mefuparib. It is a potent poly(ADP-ribose) polymerase inhibitor which exhibits strong anticancer activity and also inhibits SARS-CoV-2 in cell culture. It has a role as an anticoronaviral agent, an antineoplastic agent, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an apoptosis inducer. It contains a mefuparib(1+).
2D Structure
Properties
C17H16ClFN2O2
Molecular Formula
334.80
Molecular Weight
g/mol
334.0884
Exact Mass
Da
68.3
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
4
H-Bond Acceptors
398
Complexity
SMILES
Canonical SMILES
SMILES: CNCC1=CC=C(C=C1)C2=CC3=CC(=CC(=C3O2)C(=O)N)F.ClIsomeric SMILES
SMILES: CNCC1=CC=C(C=C1)C2=CC3=CC(=CC(=C3O2)C(=O)N)F.ClSynonyms(20)
Mefuparib hydrochloride1449746-00-2CVL-21882IYE3T3BECHEBI:1678995-Fluoro-2-(4-((methylamino)methyl)phenyl)-7-benzofurancarboxamide hydrochloride7-Benzofurancarboxamide, 5-fluoro-2-(4-((methylamino)methyl)phenyl)-, hydrochloride (1:1)MPH1 cpdRefChem:156260Mefuparib (hydrochloride)5-fluoro-2-[4-(methylaminomethyl)phenyl]-1-benzofuran-7-carboxamide;hydrochlorideMefuparib hydrochloride(CVL218)5-fluoro-2-(4-((methylamino)methyl)phenyl)benzofuran-7-carboxamide hydrochloridemefuparib HCl5-fluoro-2-{4-[(methylamino)methyl]phenyl}benzofuran-7-carboxamide hydrochloride
Data from PubChem (NCBI)
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Trials and conditions connected to Mefuparib hydrochloride
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