Cabozantinib S-malate
1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid
Molecular Identity
Cabozantinib S-malate
1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid
PubChem CID: 25102846
Cabozantinib malate is a malate salt that is the mono-(S)-malate salt of cabozantinib. A multi-tyrosine kinase inhibitor, used for the treatment of progressive, metastatic, medullary thyroid cancer. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a prodrug. It contains a cabozantinib.
2D Structure
Properties
C32H30FN3O10
Molecular Formula
635.60
Molecular Weight
g/mol
635.1915
Exact Mass
Da
194
TPSA
May have limited oral absorption
5
H-Bond Donors
12
H-Bond Acceptors
924
Complexity
SMILES
Canonical SMILES
SMILES: COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C(C(C(=O)O)O)C(=O)OIsomeric SMILES
SMILES: COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C([C@@H](C(=O)O)O)C(=O)OSynonyms(20)
Cabozantinib S-malate1140909-48-3Cabozantinib malatecabozantinib (S)-malateCabometyxXL184DR7ST46X58CHEBI:72319DTXSID60915949RefChem:1080604DTXCID501510465Cabozantinib malate (XL184)Cabozantinib (S-malate)Cabozantinib L-Malate SaltMFCD20923480
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Cabozantinib S-malate
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