Molecular Identity
Chlorothiazide
6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
PubChem CID: 2720
Chlorothiazide is 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension. It has a role as a diuretic and an antihypertensive agent.
2D Structure
Properties
C7H6ClN3O4S2
Molecular Formula
295.70
Molecular Weight
g/mol
294.9488
Exact Mass
Da
-0.2
XLogP
Drug-like (Lipinski: < 5)
135
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
6
H-Bond Acceptors
532
Complexity
SMILES
Canonical SMILES
SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2Isomeric SMILES
SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2Synonyms(20)
chlorothiazide58-94-6DiurilChlorthiazideChlorothiazidChlortiazidChlotrideFlumenChlorosalChloruritClotrideDiuresalDiurilixSaluretilWarduzide
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Chlorothiazide
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