Dabrafenib Mesylate
N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;methanesulfonic acid
Molecular Identity
Dabrafenib Mesylate
N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;methanesulfonic acid
PubChem CID: 44516822
Dabrafenib mesylate is a methanesulfonate (mesylate) salt prepared from equimolar amounts of dabrafenib and methanesulfonic acid. Used for treatment of metastatic melanoma. It has a role as an antineoplastic agent and a B-Raf inhibitor. It contains a dabrafenib.
2D Structure
Properties
C24H24F3N5O5S3
Molecular Formula
615.70
Molecular Weight
g/mol
615.0892
Exact Mass
Da
210
TPSA
May have limited oral absorption
3
H-Bond Donors
14
H-Bond Acceptors
910
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)OIsomeric SMILES
SMILES: CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)OSynonyms(20)
Dabrafenib mesylate1195768-06-9TaflinarUNII-B6DC89I63EGSK 2118436BGSK-2118436BDabrafenib methanesulfonateGSK2118436BB6DC89I63Edabrafenib monomesylateGSK-2118436B MESYLATEGSK2118436 Methane sulfonate saltGSK2118436B, methane sulfonate saltGSK-2118436 METHANESULFONATE SALTGSK-2118436B METHANESULFONATE SALT
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Dabrafenib Mesylate
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