Cudc-305
2-[[6-(dimethylamino)-1,3-benzodioxol-5-yl]sulfanyl]-1-[2-(2,2-dimethylpropylamino)ethyl]imidazo[4,5-c]pyridin-4-amine
Molecular Identity
Cudc-305
2-[[6-(dimethylamino)-1,3-benzodioxol-5-yl]sulfanyl]-1-[2-(2,2-dimethylpropylamino)ethyl]imidazo[4,5-c]pyridin-4-amine
PubChem CID: 44156921
RGRN-305 is a novel heat shock protein (HSP) 90 inhibitor; HSP90 is a chaperone that promotes the activity of a wide range of client proteins including key proinflammatory molecules involved in aberrant inflammation. RGRN-305 can target HSP90 as a novel mechanism of action in treating multiple immune-mediated inflammatory skin diseases.
2D Structure
Properties
C22H30N6O2S
Molecular Formula
442.60
Molecular Weight
g/mol
442.2151
Exact Mass
Da
3.6
XLogP
Drug-like (Lipinski: < 5)
116
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
8
H-Bond Acceptors
591
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)(C)CNCCN1C2=C(C(=NC=C2)N)N=C1SC3=CC4=C(C=C3N(C)C)OCO4Isomeric SMILES
SMILES: CC(C)(C)CNCCN1C2=C(C(=NC=C2)N)N=C1SC3=CC4=C(C=C3N(C)C)OCO4Synonyms(20)
Debio 09321061318-81-7CUDC-305DEBIO-0932Cudc305 (hsp90 inhibitor)Hsp90 inhibitor debio 09320V278OKN9GCUDC 305RefChem:128735CUDC3052-[[6-(dimethylamino)-1,3-benzodioxol-5-yl]sulfanyl]-1-[2-(2,2-dimethylpropylamino)ethyl]imidazo[4,5-c]pyridin-4-amineDebio-0932 (CUDC305)CHEMBL2419346Debio 0932 ,CUDC-3052-((6-(dimethylamino)benzo[d][1,3]dioxol-5-yl)thio)-1-(2-(neopentylamino)ethyl)-1H-imidazo[4,5-c]pyridin-4-amine
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Cudc-305
Loading drug network...