Molecular Identity
Diloxanide furoate
[4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate
PubChem CID: 19529
Diloxanide furoate is a carboxylic ester resulting from the formal condensation of the carboxy group of furan-2-carboxylic acid with the hydroxy group of 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide. It is a drug used for the treatment of asymptomatic amebiasis. It has a role as an antiamoebic agent and a prodrug. It is a tertiary carboxamide, a member of furans, a carboxylic ester and an organochlorine compound.
2D Structure
Properties
C14H11Cl2NO4
Molecular Formula
328.10
Molecular Weight
g/mol
327.0065
Exact Mass
Da
3.4
XLogP
Drug-like (Lipinski: < 5)
59.8
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
4
H-Bond Acceptors
383
Complexity
SMILES
Canonical SMILES
SMILES: CN(C1=CC=C(C=C1)OC(=O)C2=CC=CO2)C(=O)C(Cl)ClIsomeric SMILES
SMILES: CN(C1=CC=C(C=C1)OC(=O)C2=CC=CO2)C(=O)C(Cl)ClSynonyms(20)
DILOXANIDE FUROATE3736-81-0DichlofurazolFurentominAmebiazolHistomibalEntamide furoateDiloxanid furoateDiclofurazolMiforon8073 CBDTXSID8048999Diloxanidi furoasNSC-759146YP4N72IW34
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Diloxanide furoate
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