Molecular Identity
Betamethasone Dipropionate
[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
PubChem CID: 21800
Betamethasone dipropionate is a steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients. It has a role as an antipsoriatic. It is an 11beta-hydroxy steroid, a propanoate ester, a 20-oxo steroid, a steroid ester, a fluorinated steroid and a 3-oxo-Delta(1),Delta(4)-steroid. It is functionally related to a betamethasone.
2D Structure
Properties
C28H37FO7
Molecular Formula
504.60
Molecular Weight
g/mol
504.2523
Exact Mass
Da
3.6
XLogP
Drug-like (Lipinski: < 5)
107
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
8
H-Bond Acceptors
1050
Complexity
SMILES
Canonical SMILES
SMILES: CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)OC(=O)CCIsomeric SMILES
SMILES: CCC(=O)OCC(=O)[C@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)OC(=O)CCSynonyms(20)
BETAMETHASONE DIPROPIONATE5593-20-4DiprosoneDiproleneAlphatrexMaxivateBetamethasone 17,21-dipropionateRinderon DPDiprolene AFDiprospanSch 11460SernivoSch-11460DTXSID2022672beta-Methasone 17,21-dipropionate
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Betamethasone Dipropionate
Loading drug network...