Molecular Identity
Dofetilide
N-[4-[2-[2-[4-(methanesulfonamido)phenoxy]ethyl-methylamino]ethyl]phenyl]methanesulfonamide
PubChem CID: 71329
Dofetilide is a tertiary amino compound that is N-ethyl-N-methylethanamine substituted by a 4-[(methylsulfonyl)amino]phenoxy and a 4-[(methylsulfonyl)amino]phenyl group at the terminal carbon atoms respectively. It is used as an anti-arrhythmia drug. It has a role as an anti-arrhythmia drug and a potassium channel blocker. It is a sulfonamide, an aromatic ether and a tertiary amino compound.
2D Structure
Properties
C19H27N3O5S2
Molecular Formula
441.60
Molecular Weight
g/mol
441.1392
Exact Mass
Da
1.8
XLogP
Drug-like (Lipinski: < 5)
122
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
8
H-Bond Acceptors
672
Complexity
SMILES
Canonical SMILES
SMILES: CN(CCC1=CC=C(C=C1)NS(=O)(=O)C)CCOC2=CC=C(C=C2)NS(=O)(=O)CIsomeric SMILES
SMILES: CN(CCC1=CC=C(C=C1)NS(=O)(=O)C)CCOC2=CC=C(C=C2)NS(=O)(=O)CSynonyms(20)
Dofetilide115256-11-6TikosynDofetilidaDofetilidumUK-68,798UK-68798DTXSID5046433R4Z9X1N2NDbeta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidideMethanesulfonamide, N-[4-[2-[methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-CHEBI:4681DTXCID3026433N-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]methanesulfonamideMethanesulfonamide, N-(4-(2-(methyl(2-(4-((methylsulfonyl)amino)phenoxy)ethyl)amino)ethyl)phenyl)-
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Dofetilide
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