Dovitinib
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one
Molecular Identity
Dovitinib
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one
PubChem CID: 135398510
4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1,3-dihydrobenzimidazol-2-ylidene]-2-quinolinone is a N-arylpiperazine.
2D Structure
Properties
C21H21FN6O
Molecular Formula
392.40
Molecular Weight
g/mol
392.1761
Exact Mass
Da
1.6
XLogP
Drug-like (Lipinski: < 5)
90.3
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
6
H-Bond Acceptors
678
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Dovitinib405169-16-6TKI-258I35H55G906GFKI-2584-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-onedovitinibum4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene)-2,3-dihydroquinolin-2-one4-amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl)-1,2-dihydroquinolin-2-one4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene]-2,3-dihydroquinolin-2-oneRefChem:590385Dovitinib (TKI-258, CHIR-258)Dovitinib [INN]4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-oneChir 258
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Dovitinib
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