Golvatinib
1-N'-[2-fluoro-4-[[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]-4-pyridinyl]oxy]phenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Molecular Identity
Golvatinib
1-N'-[2-fluoro-4-[[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]-4-pyridinyl]oxy]phenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
PubChem CID: 16118392
Golvatinib is an aromatic ether.
2D Structure
Properties
C33H37F2N7O4
Molecular Formula
633.70
Molecular Weight
g/mol
633.2875
Exact Mass
Da
4.1
XLogP
Drug-like (Lipinski: < 5)
119
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
9
H-Bond Acceptors
1060
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Golvatinib928037-13-2E7050516Z3YP58EDTXSID402391551,1-CYCLOPROPANEDICARBOXAMIDE, N-(2-FLUORO-4-((2-(((4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDINYL)CARBONYL)AMINO)-4-PYRIDINYL)OXY)PHENYL)-N'-(4-FLUOROPHENYL)-golvatinibumN'-(2-fluoro-4-(2-((4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)amino)pyridin-4-yl)oxyphenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideN'-[2-fluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideRefChem:144121DTXCID60161646c-Met/VEGFR-2 Kinase Inhibitor E7050N'1-(2-fluoro-4-((2-((4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)amino)pyridin-4-yl)oxy)phenyl)-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideGolvatinib (E7050)E-7050
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Golvatinib
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