Indisulam
4-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
Molecular Identity
Indisulam
4-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
PubChem CID: 216468
Indisulam is a chloroindole that is 3-chloro-1H-indole substituted by a [(4-sulfamoylphenyl)sulfonyl]nitrilo group at position 7. It is a carbonic anhydrase inhibitor and a potential anti-cancer agent currently in clinical development. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor and an antineoplastic agent. It is a sulfonamide, an organochlorine compound and a chloroindole.
2D Structure
Properties
C14H12ClN3O4S2
Molecular Formula
385.80
Molecular Weight
g/mol
384.9958
Exact Mass
Da
1.8
XLogP
Drug-like (Lipinski: < 5)
139
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
6
H-Bond Acceptors
650
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Indisulam165668-41-7E7070N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamideE-7070N1-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamideindisulamumWJ98J3NM90CHEBI:145431DTXSID50168008N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamideN-(3-chloro-7-indolyl)-1,4-benzenedisulfonamideRefChem:790922DTXCID2090499N-(3-Chloro-7-indoyl)-1,4-Benzenedisulfonamide
Data from PubChem (NCBI)
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