Molecular Identity
Rivastigmine
[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
PubChem CID: 77991
Rivastigmine is a carbamate ester obtained by formal condensation of the carboxy group of ethyl(methyl)carbamic acid with the phenolic OH group of 3-[(1S)-1-(dimethylamino)ethyl]phenol. A reversible cholinesterase inhibitor. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor, a cholinergic drug and a neuroprotective agent. It is a carbamate ester and a tertiary amino compound. It is a conjugate base of a rivastigmine(1+).
2D Structure
Properties
C14H22N2O2
Molecular Formula
250.34
Molecular Weight
g/mol
250.1681
Exact Mass
Da
2.3
XLogP
Drug-like (Lipinski: < 5)
32.8
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
3
H-Bond Acceptors
269
Complexity
SMILES
Canonical SMILES
SMILES: CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)CIsomeric SMILES
SMILES: CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)CSynonyms(20)
rivastigmine123441-03-2PrometaxENA 713 free baseNimvastidRivastigmine Tevarivastigmine hexalRivastigminaRivastigmine sandozSDZ-ENA-713SDZ-212-713ONO-2540PKI06M3IW0m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate(S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Rivastigmine
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