Memantine Hydrochloride
3,5-dimethyladamantan-1-amine;hydrochloride
Molecular Identity
Memantine Hydrochloride
3,5-dimethyladamantan-1-amine;hydrochloride
PubChem CID: 181458
Memantine hydrochloride is a hydrochloride obtained by reaction of memantine with one equivalent of hydrochloric acid. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. It has a role as an antidepressant, an antiparkinson drug, a dopaminergic agent, a NMDA receptor antagonist and a neuroprotective agent. It contains a memantinium(1+).
2D Structure
Properties
C12H22ClN
Molecular Formula
215.76
Molecular Weight
g/mol
215.1441
Exact Mass
Da
26
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
1
H-Bond Acceptors
240
Complexity
SMILES
Canonical SMILES
SMILES: CC12CC3CC(C1)(CC(C3)(C2)N)C.ClIsomeric SMILES
SMILES: CC12CC3CC(C1)(CC(C3)(C2)N)C.ClSynonyms(20)
MEMANTINE HYDROCHLORIDE41100-52-1Memantine HCL3,5-dimethyladamantan-1-amine hydrochloride3,5-Dimethyl-1-adamantanamine hydrochlorideAkatinolNamenda XRMemaryMemantine MylanMemantine MerzMemantine AccordMemantine LEK1-Amino-3,5-dimethyladamantane HydrochlorideAcrescentBalaxur
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Memantine Hydrochloride
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