Molecular Identity
Eflornithine
2,5-diamino-2-(difluoromethyl)pentanoic acid
PubChem CID: 3009
Eflornithine is a fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2. It has a role as a trypanocidal drug. It is a fluoroamino acid and an alpha-amino acid. It is functionally related to an ornithine.
2D Structure
Properties
C6H12F2N2O2
Molecular Formula
182.17
Molecular Weight
g/mol
182.0867
Exact Mass
Da
-2.9
XLogP
Drug-like (Lipinski: < 5)
89.3
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
6
H-Bond Acceptors
166
Complexity
SMILES
Canonical SMILES
SMILES: C(CC(C(F)F)(C(=O)O)N)CNIsomeric SMILES
SMILES: C(CC(C(F)F)(C(=O)O)N)CNSynonyms(20)
EFLORNITHINE70052-12-9dfmo2-(Difluoromethyl)ornithine2,5-diamino-2-(difluoromethyl)pentanoic acidEflornitinaEflornithinumalpha-Difluoromethylornithine2-(Difluoromethyl)-DL-ornithinealpha-(Difluoromethyl)-DL-ornithineOrnithine, 2-(difluoromethyl)-DL-alpha-DifluoromethylornithineDL-Ornithine, 2-(difluoromethyl)-ZQN1G5V6SRCHEBI:41948
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Eflornithine
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