Molecular Identity
Epigallocatechin Gallate
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
PubChem CID: 65064
(-)-epigallocatechin 3-gallate is a gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of ()-epigallocatechin. It has a role as a geroprotector, an antioxidant, an antineoplastic agent, a neuroprotective agent, a Hsp90 inhibitor, an apoptosis inducer and a plant metabolite. It is a polyphenol, a gallate ester and a member of flavans. It is functionally related to a (-)-epigallocatechin.
2D Structure
Properties
C22H18O11
Molecular Formula
458.40
Molecular Weight
g/mol
458.0849
Exact Mass
Da
1.2
XLogP
Drug-like (Lipinski: < 5)
197
TPSA
May have limited oral absorption
8
H-Bond Donors
11
H-Bond Acceptors
667
Complexity
SMILES
Canonical SMILES
SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)OIsomeric SMILES
SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)OSynonyms(20)
(-)-Epigallocatechin gallate989-51-5EGCGEpigallocatechin gallateEpigallocatechin-3-gallateTea catechin(-)-Epigallocatechin-3-o-gallateTeavigo(-)-Epigallocatechol gallateDTXSID1029889L-Epigallocatechin gallatePF-EGCg 90NVP-XAA 723BQM438CTELepigallocatechin-3-O-gallate
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Epigallocatechin Gallate
Loading drug network...