Erdafitinib
N'-(3,5-dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine
Molecular Identity
Erdafitinib
N'-(3,5-dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine
PubChem CID: 67462786
Erdafitinib is a Kinase Inhibitor. The mechanism of action of erdafitinib is as a Fibroblast Growth Factor Receptor Inhibitor, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A4 Inducer, and P-Glycoprotein Inhibitor, and Organic Cation Transporter 2 Inhibitor.
2D Structure
Properties
C25H30N6O2
Molecular Formula
446.50
Molecular Weight
g/mol
446.2430
Exact Mass
Da
3.2
XLogP
Drug-like (Lipinski: < 5)
77.3
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
7
H-Bond Acceptors
583
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Erdafitinib1346242-81-6Balversa890E37NHMVDTXSID0010279361,2-Ethanediamine, N1-(3,5-dimethoxyphenyl)-N2-(1-methylethyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl)-N'-(3,5-dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamineerdafitinibumN'-(3,5-dimethoxyphenyl)-N'-(3-(1-methylpyrazol-4-yl)quinoxalin-6-yl)-N-propan-2-ylethane-1,2-diamineN1-(3,5-Dimethoxyphenyl)-N2-(1-methylethyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl)-1,2-ethanediamineN1-(3,5-Dimethoxyphenyl)-N2-(1-methylethyl)-N1-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-1,2-ethanediamineRefChem:57639DTXCID201513503JNJ-42756493N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Data from PubChem (NCBI)
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Drug Network
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