Eszopiclone
[(7S)-6-(5-chloro-2-pyridinyl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
Molecular Identity
Eszopiclone
[(7S)-6-(5-chloro-2-pyridinyl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
PubChem CID: 969472
Eszopiclone is the (5S)- (active) enantiomer of zopiclone. Unlike almost all other hypnotic sedatives, which are approved only for the relief of short-term (6-8 weeks) insomnia, eszopiclone is approved by the U.S. Food and Drug Administration for long-term use. It has a role as a central nervous system depressant and a sedative. It is an enantiomer of a (5R)-zopiclone.
2D Structure
Properties
C17H17ClN6O3
Molecular Formula
388.80
Molecular Weight
g/mol
388.1051
Exact Mass
Da
0.5
XLogP
Drug-like (Lipinski: < 5)
91.8
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
7
H-Bond Acceptors
573
Complexity
SMILES
Canonical SMILES
SMILES: CN1CCN(CC1)C(=O)OC2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)ClIsomeric SMILES
SMILES: CN1CCN(CC1)C(=O)O[C@H]2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)ClSynonyms(20)
Eszopiclone138729-47-2Lunesta(S)-ZopicloneEstorraEsopiclone(+)-ZopicloneEszopiclonEszopiclone civSEP-190eszopiclonaDTXSID8046086UZX80K71OE(+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate[(7S)-6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
Data from PubChem (NCBI)
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