Molecular Identity
ethosuximide
3-ethyl-3-methylpyrrolidine-2,5-dione
PubChem CID: 3291
Ethosuximide is a dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures. It has a role as a geroprotector, a T-type calcium channel blocker and an anticonvulsant. It is a dicarboximide and a pyrrolidinone.
2D Structure
Properties
C7H11NO2
Molecular Formula
141.17
Molecular Weight
g/mol
141.0790
Exact Mass
Da
0.4
XLogP
Drug-like (Lipinski: < 5)
46.2
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
2
H-Bond Acceptors
188
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
ethosuximide77-67-8ZarontinEtosuximida2-Ethyl-2-methylsuccinimide3-Ethyl-3-methylpyrrolidine-2,5-dioneEthosuxidePyknolepsinumEmesideSuxilepEthosuccimideEthosuccinimideAtysmalSuxinutinEtosuximid
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to ethosuximide
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