Molecular Identity
flufenamic acid
2-[3-(trifluoromethyl)anilino]benzoic acid
PubChem CID: 3371
Flufenamic acid is an aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic and an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. It is an aromatic amino acid and an organofluorine compound. It is functionally related to an anthranilic acid, a (trifluoromethyl)benzene and a diphenylamine. It is a conjugate acid of a flufenamate.
2D Structure
Properties
C14H10F3NO2
Molecular Formula
281.23
Molecular Weight
g/mol
281.0664
Exact Mass
Da
5.2
XLogP
Above Lipinski threshold
49.3
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
6
H-Bond Acceptors
346
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
flufenamic acid530-78-9ArlefFluphenamic acidAchless2-((3-(Trifluoromethyl)phenyl)amino)benzoic acidN-(3-Trifluoromethylphenyl)anthranilic acidAcido flufenamicoFlufenaminsaeureMeralen2-{[3-(trifluoromethyl)phenyl]amino}benzoic acidAcide flufenamiqueCI 440NSC-826992-[3-(Trifluoromethyl)anilino]benzoic acid
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to flufenamic acid
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