TAFAMIDIS
2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
Molecular Identity
TAFAMIDIS
2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
PubChem CID: 11001318
Tafamidis is a member of the class of 1,3-benzoxazoles that is 1,3-benzoxazole-6-carboxylic acid in which the hydrogen at position 2 is replaced by a 3,5-dichlorophenyl group. Used (as its meglumine salt) for the amelioration of transthyretin-related hereditary amyloidosis. It has a role as a central nervous system drug. It is a dichlorobenzene, a monocarboxylic acid and a member of 1,3-benzoxazoles. It is a conjugate acid of a tafamidis(1-).
2D Structure
Properties
C14H7Cl2NO3
Molecular Formula
308.10
Molecular Weight
g/mol
306.9803
Exact Mass
Da
4.2
XLogP
Drug-like (Lipinski: < 5)
63.3
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
4
H-Bond Acceptors
371
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
TAFAMIDIS594839-88-0Vyndamax2-(3,5-Dichlorophenyl)-1,3-Benzoxazole-6-Carboxylic AcidFX-1006tafamidisum8FG9H9D31J2-(3,5-dichlorophenyl)benzoxazole-6-carboxylic acidCHEBI:78538FX1006FX-1005DTXSID002081856-Benzoxazolecarboxylic acid, 2-(3,5-dichlorophenyl)-RefChem:56085DTXCID20130676
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to TAFAMIDIS
Loading drug network...