Favipiravir
5-fluoro-2-oxo-1H-pyrazine-3-carboxamide
Molecular Identity
Favipiravir
5-fluoro-2-oxo-1H-pyrazine-3-carboxamide
PubChem CID: 492405
Favipiravir is a member of the class of pyrazines that is pyrazine substituted by aminocarbonyl, hydroxy and fluoro groups at positions 2, 3 and 6, respectively. It is an anti-viral agent that inhibits RNA-dependent RNA polymerase of several RNA viruses and is approved for the treatment of influenza in Japan. It has a role as an anticoronaviral agent, an EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor and an antiviral drug. It is a primary carboxamide, an organofluorine compound and a hydroxypyrazine.
2D Structure
Properties
C5H4FN3O2
Molecular Formula
157.10
Molecular Weight
g/mol
157.0288
Exact Mass
Da
-0.6
XLogP
Drug-like (Lipinski: < 5)
84.6
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
4
H-Bond Acceptors
281
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Favipiravir259793-96-9avigan6-FLUORO-3-HYDROXYPYRAZINE-2-CARBOXAMIDET-7055-fluoro-2-oxo-1H-pyrazine-3-carboxamide6-fluoro-3-hydroxy-2-pyrazinecarboxamideT 705FapilavirFavilavirT-705 cpdEW5GL2X7E0T7052-Pyrazinecarboxamide, 6-fluoro-3-hydroxy-CHEBI:134722
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Favipiravir
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