Florbetapir F-18
4-[(E)-2-[6-[2-[2-(2-(18F)fluoroethoxy)ethoxy]ethoxy]-3-pyridinyl]ethenyl]-N-methyl(18F)aniline
Molecular Identity
Florbetapir F-18
4-[(E)-2-[6-[2-[2-(2-(18F)fluoroethoxy)ethoxy]ethoxy]-3-pyridinyl]ethenyl]-N-methyl(18F)aniline
PubChem CID: 24822371
Florbetapir F-18 is an aromatic ether consisting of a pyridine ring substituted at position 2 by a 2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy group and at position 5 and a 2-(4-methylaminophenyl)vinyl group. A positron emission tomography imaging ligand for the detection of amyloid aggregation associated with Alzheimer disease. It has a role as a radioactive imaging agent. It is a member of pyridines, an aromatic ether, an organofluorine compound, a substituted aniline and a (18)F radiopharmaceutical.
2D Structure
Properties
C20H25FN2O3
Molecular Formula
359.40
Molecular Weight
g/mol
359.1875
Exact Mass
Da
3.5
XLogP
Drug-like (Lipinski: < 5)
52.6
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
6
H-Bond Acceptors
376
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Florbetapir F-18florbetapir (18F)AmyvidFlorbetapirFlorbetapir F 18956103-76-718F-AV-4518F-AV45Florbetapir(18-f)Florbetapir, f-18florbetapir F18(18F)AV-45AV-45 F-186W15Z5R0RUAv45 f-18
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Florbetapir F-18
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