Molecular Identity
5-Fluorocytosine
6-amino-5-fluoro-1H-pyrimidin-2-one
PubChem CID: 3366
Flucytosine is an organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections. It has a role as a prodrug. It is an organofluorine compound, a pyrimidone, an aminopyrimidine, a nucleoside analogue and a pyrimidine antifungal drug. It is functionally related to a cytosine.
2D Structure
Properties
C4H4FN3O
Molecular Formula
129.09
Molecular Weight
g/mol
129.0338
Exact Mass
Da
-0.9
XLogP
Drug-like (Lipinski: < 5)
67.5
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
3
H-Bond Acceptors
208
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
5-Fluorocytosineflucytosine2022-85-7FluorocytosineAncobonAncotilFluocytosine5-FluorocystosineFlucytosin5-FluorocytosinFluorcytosineAlcobonFlucytosinum4-Amino-5-fluoropyrimidin-2(1H)-oneRo 2-9915
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to 5-Fluorocytosine
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