Gdc-0152
(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-(4-phenylthiadiazol-5-yl)pyrrolidine-2-carboxamide
Molecular Identity
Gdc-0152
(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-(4-phenylthiadiazol-5-yl)pyrrolidine-2-carboxamide
PubChem CID: 46940575
2D Structure
Properties
C25H34N6O3S
Molecular Formula
498.60
Molecular Weight
g/mol
498.2413
Exact Mass
Da
3.4
XLogP
Drug-like (Lipinski: < 5)
145
TPSA
May have limited oral absorption
3
H-Bond Donors
7
H-Bond Acceptors
743
Complexity
SMILES
Canonical SMILES
SMILES: CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=NS3)C4=CC=CC=C4)NCIsomeric SMILES
SMILES: C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C(=O)NC3=C(N=NS3)C4=CC=CC=C4)NCSynonyms(20)
GDC-0152873652-48-34KW1M48SHSDTXSID00236307(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-(4-phenylthiadiazol-5-yl)pyrrolidine-2-carboxamide(2S)-1-[(2S)-2-cyclohexyl-2-[(2S)-2-(methylamino)propanamido]acetyl]-N-(4-phenyl-1,2,3-thiadiazol-5-yl)pyrrolidine-2-carboxamide(2S)-1-((2S)-2-cyclohexyl-2-(((2S)-2-(methylamino)propanoyl)amino)acetyl)-N-(4-phenylthiadiazol-5-yl)pyrrolidine-2-carboxamide(2S)-1-((2S)-2-cyclohexyl-2-((2S)-2-(methylamino)propanamido)acetyl)-N-(4-phenyl-1,2,3-thiadiazol-5-yl)pyrrolidine-2-carboxamideRefChem:142761Smac Mimetic GDC-0152IAP Antagonist GDC-0152DTXCID60158798GDC-0152 free baseUNII-4KW1M48SHS(s)-1-((s)-2-cyclohexyl-2-((s)-2-(methylamino)propanamido)acetyl)-N-(4-phenyl-1,2,3-thiadiazol-5-yl)pyrrolidine-2-carboxamide
Data from PubChem (NCBI)
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