Gw-493838
(2S,3S,4R,5R)-2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-[6-(4-chloro-2-fluoroanilino)purin-9-yl]oxolane-3,4-diol
Molecular Identity
Gw-493838
(2S,3S,4R,5R)-2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-[6-(4-chloro-2-fluoroanilino)purin-9-yl]oxolane-3,4-diol
PubChem CID: 9810927
2D Structure
Properties
C21H21ClFN7O4
Molecular Formula
489.90
Molecular Weight
g/mol
489.1328
Exact Mass
Da
2.2
XLogP
Drug-like (Lipinski: < 5)
144
TPSA
May have limited oral absorption
3
H-Bond Donors
11
H-Bond Acceptors
723
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)(C)C1=NN=C(O1)C2C(C(C(O2)N3C=NC4=C(N=CN=C43)NC5=C(C=C(C=C5)Cl)F)O)OIsomeric SMILES
SMILES: CC(C)(C)C1=NN=C(O1)[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)NC5=C(C=C(C=C5)Cl)F)O)OSynonyms(20)
GW-49383893OG0JL22OGW493838(2S,3S,4R,5R)-2-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)-5-(6-(4-chloro-2-fluoro-anilino)purin-9-yl)tetrahydrofuran-3,4-diolUNII-93OG0JL22O(2R,3R,4S,5S)-2-(6-((4-CHLORO-2-FLUOROPHENYL)AMINO)-9H-PURIN-9-YL)-5-(5-(1,1-DIMETHYLETHYL)-1,3,4-OXADIAZOL-2-YL)TETRAHYDRO-3,4-FURANDIOL3,4-FURANDIOL, 2-(6-((4-CHLORO-2-FLUOROPHENYL)AMINO)-9H-PURIN-9-YL)-5-(5-(1,1-DIMETHYLETHYL)-1,3,4-OXADIAZOL-2-YL)TETRAHYDRO-, (2R,3R,4S,5S)-(2R,3R,4S,5S)-2-{6-[(4-chloro-2-fluorophenyl)amino]-9H-purin-9-yl}-5-[5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2-yl]tetrahydro-3,4-furandiolRefChem:144816(2S,3S,4R,5R)-2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-(6-((4-chloro-2-fluorophenyl)amino)-9H-purin-9-yl)oxolane-3,4-diol(2S,3S,4R,5R)-2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-{6-[(4-chloro-2-fluorophenyl)amino]-9H-purin-9-yl}oxolane-3,4-diol689-185-2493838253124-46-8GW-493838 X
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Gw-493838
Loading drug network...